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Comparison of Blood Gases During Transport Using Two Methods of Ventilatory Support.

Hurst JM, Davis K, Branson RD, Johannigman JA. Journal of Trauma. 1989; 29: Pages 1637-1640.

Having previously shown that all members of the health care team (physicians, respiratory therapists and nurses) tended to ventilate patients at a more rapid rate and lower tidal volume during manual resuscitation, the authors examined 28 critically-ill patients (19 males and 9 females with a mean age of 27 +/- 12 years) requiring ventilation during transport, in a prospective, randomized fashion. Manual ventilation with a bag-valve resuscitator was compared to that provided by a transport ventilator. Patients were ventilated to their destination with one method and returned with the other (Average transport time 9 +/- 3 mins during manual ventilation and 8 +/- 3 mins using transport ventilator). While oxygenation remained stable under both methods, all patients showed a marked respiratory alkalosis (pH increased 7.39 to 7.51 and pCO2 decreased from 39 to 30 mmHg) after manual ventilation. No appreciable changes in pH or pCO2 were noted with the transport ventilator. No patient suffered hemodynamic instability although two patients developed cardiac arrythmias (supraventricular tachycardia) during manual ventilation. The authors discuss the myriad of complications associated with sudden hypocarbia and respiratory alkalosis, such as that experienced during the manual ventilation protocol. These include impaired oxygen delivery at the tissue level, reduced cerebral and coronary blood flow, increased susceptibility to arrythmias and hypotension, and coronary vasospasm. They conclude that transportation of patients requiring diagnostic studies will continue to represent a challenge. When ventilatory support is required during transport, a transport ventilator produces reliable control of ventilation.